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Usda Makes Preliminary Diagnosis Of Bse

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-------- Original Message --------
Subject: USDA MAKES PRELIMINARY DIAGNOSIS OF BSE
Date: Tue, 23 Dec 2003 18:37:54 -0600
From: "Terry S. Singeltary Sr." <[email protected]>
To: BSE-L <[email protected]>
CC: CJDVOICE <[email protected]>, BLOODCJD <[email protected]>, [email protected]


Release No. 0432.03
Alisa Harrison (202) 720-4623
Julie Quick (202) 720-4623

USDA MAKES PRELIMINARY DIAGNOSIS OF BSE

WASHINGTON, Dec. 23, 2003-Agriculture Secretary Ann M. Veneman today announced that the U.S. Department of Agriculture has diagnosed a presumptive positive case of bovine spongiform encephalopathy (BSE) in an adult Holstein cow in the state of Washington.

"Despite this finding, we remain confident in the safety of our beef supply," Veneman said. "The risk to human health from BSE is extremely low."

Because the animal was non-ambulatory (downer) at slaughter, samples were taken Dec. 9 as part of USDA's targeted BSE surveillance system. The samples were sent to USDA's National Veterinary Services Laboratory in Ames, Iowa. Positive results were obtained by both histology (a visual examination of brain tissue via microscope) and immunohistochemistry (the gold standard for BSE testing that detects prions through a staining technique). Test results were returned on Dec. 22 and retested on Dec 23.

USDA has initiated a comprehensive epidemiological investigation working with state, public health, and industry counterparts to determine the source of the disease. USDA will also work with the Food and Drug Administration as they conduct animal feed investigations, the primary pathway for the spread of BSE.

This investigation has begun while the sample is being sent to the world reference laboratory in England for final confirmation. USDA will take the actions in accordance with its BSE response plan, which was developed with considerable input from federal, state and industry stakeholders.

BSE is a progressive neurological disease among cattle that is always fatal. It belongs to a family of diseases known as transmissible spongiform encephalopathies. Also included in that family of illnesses is the human disease, variant Creutzfeldt-Jakob Disease (vCJD), which is believed to be caused by eating neural tissue, such as brain and spinal cord, from BSE-affected
cattle. USDA has determined that the cow comes from a farm in Washington State and as part of the USDA response plan, the farm has been quarantined. After the animal was slaughtered, the meat was sent for processing and USDA's Food Safety and Inspection Service is working to determine the final disposition of products from the animal.

For more information visit www.usda.gov.

#

USDA News
[email protected]
202 720-9035
==============

Docket Management Docket: 02N-0273 - Substances Prohibited From Use in
Animal Food or Feed; Animal Proteins Prohibited in Ruminant Feed
Comment Number: EC -10
Accepted - Volume 2

http://www.fda.gov/ohrms/dockets/dailys/03/Jan03/012403/8004be07.html

PART 2

http://www.fda.gov/ohrms/dockets/dailys/03/Jan03/012403/8004be09.html

Asante/Collinge et al, that BSE transmission to the 129-methionine genotype can lead to an alternate phenotype that is indistinguishable from type 2 PrPSc, the commonest _sporadic_ CJD;

http://www.fda.gov/ohrms/dockets/ac/03/slides/3923s1_OPH.htm

PDF]Freas, William TSS SUBMISSION
File Format: PDF/Adobe Acrobat -
Page 1. J Freas, William From: Sent: To: Subject: Terry S. Singeltary
Sr. [[email protected]] Monday, January 08,200l 3:03 PM freas ...

http://www.fda.gov/ohrms/dockets/ac/01/slides/3681s2_09.pdf

TSS
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The cow has been traced to Canada.

Investigators Trace Diseased Cow to Canada

Dec 27, 12:08 PM (ET)

By EMILY GERSEMA

(AP) Workers of the Nuevo Carnic slaughterhouse select beef before packing it in Managua, Nicaragua on...
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WASHINGTON (AP) - The Holstein infected with mad cow disease in Washington state was imported into the United States from Canada about two years ago, federal investigators tentatively concluded Saturday.

Dr. Ron DeHaven, chief veterinarian for the Agriculture Department, said Canadian officials have provided records that indicate the animal was one of a herd of 74 cattle that were shipped from Alberta, Canada, into this country in August 2001 at Eastport, Idaho. It joined the Washington state herd in October 2001.

"These animals were all dairy cattle and entered the U.S. only about two or two-and-a-half years ago, so most of them are still likely alive," DeHaven said.

DeHaven emphasized that just because the sick cow was a member of that herd, it does not mean that all 74 animals are infected.


(AP) Cows feed near a recently-posted no treapassing sign at the dairy farm Sunny Dene Ranch Friday,...
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Canada, which found a case mad cow disease in Alberta in May.

Just days after the discovery of the nation's first case of mad cow disease, the United States has lost nearly all of its beef exports as more than a dozen countries stopped buying American beef as insurance against potential infection.

Based on the Canadian records, the diseased cow was 6 1/2-years-old - older than U.S. officials had thought, DeHaven said. U.S. papers on the cow said she was 4- or 4 1/2-years-old.

The age is significant because the United States and Canada have banned feed that could be the source of infection since 1997.

Farmers used to feed their animals meal containing tissue from other cattle and livestock to fatten them. Health officials in both countries banned such feed because infected tissue - such as the brain and spinal cord - could be in the meal.


(AP) The dairy farm Sunny Dene Ranch is shown Friday morning, Dec. 26, 2003, in Mabton, Wash. The farm...
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The Agriculture Department also has recalled an estimated 10,000 pounds of meat cut from the infected cow and from 19 other cows all slaughtered Dec. 9 at Vern's Moses Lake Meat Co., in Moses Lake, Wash.

Ken Peterson, of the department's Food Safety and Inspection Service, said officials still are trying to track down the meat.

He and other department officials have stressed that the U.S. meat is still considered safe because the animal's brain and spinal cord were removed before the meat was processed.

Officials say the slaughtered cow was deboned at Midway Meats in Centralia, Ore., and the meat - though no contaminated spinal or brain tissue - was sent to two other plants in the region, identified as Willamette and Interstate Meat, both near Portland, Ore.

Mad cow disease, formally known as bovine spongiform encephalopathy, is a public health concern because it is related to a human disease, variant Creutzfeldt-Jakob. In Britain, 143 people died of the human illness after an outbreak of mad cow in the 1980s. People can get it if they eat meat containing tissue from the brain and spine of an infected cow.


(AP) Mabton, Wash., Mayor David Conradt speaks with a reporter in front of city hall Friday, Dec. 26,...
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The animal most likely became sick from eating contaminated feed, so investigators with the Food and Drug Administration, which regulates animal feed, are tracking down what it ate. That is a difficult task because the cow may have gotten the disease years ago, long before it showed signs that it was sick.

Dr. Stephen Sundlof, head of the FDA's Center for Veterinary Medicine, said the agency also is trying to account for all of the products made from the cow. This includes items like soap and soil.

FDA is "trying to trace down any byproducts from processing of the cow to keep it from getting into other products that FDA regulates, including feeds," Sundlof said.

Gregg Doud, an economist for the Denver-based National Cattlemen's Beef Association, said Friday that the United States stands to lose at least $6 billion a year in exports and falling domestic prices because of the sick cow.

"We've lost roughly 90 percent of our export market just in the last three days," Doud said.


(AP) Dan Senn walks past feeding cows at the dairy farm Sunny Dene Ranch Friday, Dec. 26, 2003, in...
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Keith Collins, the Agriculture Department's chief economist, said the market probably will not see the full economic impact of the mad cow case until trading intensifies after the holidays. He has said that 10 percent of U.S. beef is exported.

Japan, South Korea and Mexico are among the top buyers that banned American beef imports this week after the U.S. government announced it had found a cow in Washington state sick with the brain-wasting illness.

An international lab in England confirmed that diagnosis Thursday. By Saturday, when tiny Kuwait joined the import ban, the list of countries had topped two dozen.

A U.S. delegation is leaving Saturday for Japan, which takes about one-third of all U.S. beef exports, and possibly other Asian countries that imposed bans on American meat and livestock this week. The Treasury Department said it is monitoring developments.

Federal officials on Friday quarantined a herd of 400 bull calves, one of which is an offspring of the sick cow. During its life, the infected cow bore three calves.

One calf is still at the same dairy near Mabton, Wash., that was the final home of the diseased Holstein cow. That herd was quarantined earlier. Another calf is at a bull calf feeding operation in Sunnyside, Wash., and a third died shortly after being born in 2001, said DeHaven.

"There is the potential that the infected cow could pass the disease onto its calves," he said. No decision has been made on destroying the herds, he said.

Investigators are focused on finding the birth herd of the cow, since it likely was infected several years ago from eating contaminated feed, DeHaven said. Scientists say the incubation period for the disease in cattle is four or five years.

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